Flow Cytometry Data Analysis: Basic Concepts and Statistics

Paperback / softback

Main Details

Title Flow Cytometry Data Analysis: Basic Concepts and Statistics
Authors and Contributors      By (author) James V. Watson
Physical Properties
Format:Paperback / softback
Pages:300
Dimensions(mm): Height 230,Width 155
Category/GenreScientific equipment, experiments and techniques
Cellular biology (cytology)
ISBN/Barcode 9780521019705
ClassificationsDewey:571.6028
Audience
Professional & Vocational
Illustrations 41 Tables, unspecified; 5 Halftones, unspecified; 134 Line drawings, unspecified

Publishing Details

Publisher Cambridge University Press
Imprint Cambridge University Press
Publication Date 15 September 2005
Publication Country United Kingdom

Description

Flow cytometry is now well established in research laboratories and is gaining increasing use in clinical medicine and pathology. The technique enables multiple simultaneous light scatter and fluorescence measurements to be made at the individual cell level at very rapid rates and results in very large quantities of data being collected. Data, however, is just a series of numbers which have to be converted to information which, in turn, must be shown to have meaning. This is the most important single aspect of flow cytometry but it has received relatively little attention. One of the frequently voiced advantages of the technology is that it produces 'good statistics' because large numbers of cells have been analysed. However, it is not very often that confidence limits are placed on results, hence the reader has little or no feel for the inherent variability in the information produced. This book covers very basic number handling techniques, regression analysis, probability functions, statistical tests and methods of analysing dynamic processes. All those who use flow cytometry in their research will find this book an invaluable guide to interpreting the data produced by flow cytometers.

Reviews

"I recommend this book as an introduction to statistics for the mathematically intimidated and as a gateway into flow cytometry for the mathematically sophisticated...the book should prove useful." Cancer Bulletin