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Physiological Pharmaceutics: Barriers to Drug Absorption

Paperback / softback

Main Details

Title Physiological Pharmaceutics: Barriers to Drug Absorption
Authors and Contributors      By (author) C. G. Wilson
By (author) Clive Washington
By (author) Clive Wilson
By (author) Neena Washington
Physical Properties
Format:Paperback / softback
Pages:328
Dimensions(mm): Height 254,Width 178
Category/GenrePhysiology
ISBN/Barcode 9780748406104
ClassificationsDewey:615.7
Audience
Undergraduate
Postgraduate, Research & Scholarly
Professional & Vocational

Publishing Details

Publisher Taylor & Francis Ltd
Imprint Taylor & Francis Ltd
Publication Date 21 December 2000
Publication Country United Kingdom

Description

In recent years, the emphasis in drug development has been the design of new delivery systems rather than new drugs. It is the aim of innovative pharmaceutical scientists to design the new dosage forms to overcome the body's barrier mechanisms which have specifically evolved to exclude foreign material. This book provides an integrated approach to the study of drug formulation in the body with the emphasis on the formulation variables rather than the drugs. The link between physiology and pharmaceutics is presented to give an essential background of biological principles for the pharmacy student, pharmaceutical formulator and healthcare professional. Complex mathematical aspects of physical chemistry have been avoided to facilitate understanding, enabling the reader to concentrate on how the biological environment affects the performance of the drugs and dosage forms. As the majority of drugs are administered via the oral route a large proportion of the book is devoted to the gastrointestinal tract and the variation in the capacity for drug absorption which occurs along its length. Transdermal, ocular, pulmonary and nasal drug delivery are discussed in detail. New chapters in the book include 'Vaginal drug delivery', the 'Blood brain barrier' and 'Parenteral drug delivery'.

Author Biography

Washington; Neena University of Nottingham Medical School, England, UK,Washington; Clive AstraZeneca,Wilson; Clive University of Strathclyde, UK,

Reviews

'Provides essential information...There is no equivalent source work.' '...a worthwhile and valuable contribution to this area.'