Chemical Genomics

Description

Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of the basic principles of chemical biology and chemical genomics. This is followed by a technical section that describes the sources of small-molecule chemicals; the basics of high-throughput screening technologies; and various bioassays for biochemical-, cellular- and organism-based screens. The final chapters connect the chemical genomics field with personalized medicine and the druggable genome for future discovery of new therapeutics. This book will be valuable to researchers, professionals and graduate students in many fields, including biology, biomedicine and chemistry.

Haian Fu is a Professor of Pathology, Hematology, and Medical Oncology at Emory University School of Medicine. He also serves as director of the Chemical Biology Discovery Center and co-director of the Discovery and Developmental Therapeutics Program at the Winship Cancer Institute at Emory University. His research focuses on protein-protein interactions in signal transduction pathways that control cell survival and death in normal and cancer cells. He serves on the editorial board of several scientific journals, including Current Chemical Genomics. He edited Protein-Protein Interactions: Methods and Applications (2004). Dr Fu has been recognized by various honors including the PhRMA Faculty Development Award, the Burroughs Wellcome Fund New Investigator Award, the GRA Distinguished Investigator Award and the Georgia Cancer Coalition Distinguished Cancer Scholar. He is also a recipient of the Award for Excellence in Mentorship by the Emory Graduate Division of Biological and Biomedical Sciences (2000) and the Emory Pharmacology Teaching Excellence Award (2006).

'Author Haian Fu has effectively assembled his textbook, Chemical Genomics, in a manner that is easy to comprehend and builds a basic understanding of chemical genomics.' Danielle Gerhard, Yale Journal of Biology and Medicine